It is possible to connect powerlines with different data rates and brands as our devices use the HomePlug AV standard which makes any device compatible no matter the brand or data rates. For instance, you can connect a Powerline 600 Mini with a powerline 500 or 600 as they have similar data rates. That is why, we strongly recommend not to connect a Powerline 600 Mini with powerline 1000, 1200, 1300 or 2000 which have higher data rates than the one of the Powerline 600 Mini, In addition, a Powerline 600 Mini can be connected to powerline 600 of different brands, but we cannot guarantee that it will work properly with powerlines 600 from other brands, as there may be software differences.